AO3C2849-mike-scm-smoke-1-2000-3

X-Ray Crystallography

X-Ray crystallography is the most common technique used for determining the high resolution structures of macromolecules, and is a powerful approach for understanding how proteins and nucleic acids function.  Many laboratories at UNC use crystallography as an important tool to study a variety of  research areas including drug discovery, protein engineering, cell signaling, enzymology, and cytoskeleton research.  The crystallography core facility at UNC (http://www.med.unc.edu/csb/mx) provides equipment and robots for crystallization, automated X-ray diffraction screening, and provides access to SERCAT beamline at Argonne National Laboratoy.

Faculty who use crystallography as a primary research tool:

Nicholas Brown

Charles Carter

Hengming Ke

Brian Kuhlman

Robert McGinty

Matthew Redinbo

Kevin Slep

John Sondek