Training Overview

We provide our trainees with a rigorous grounding in the basic principles of molecular and thermodynamic descriptions of macromolecules through the 650 series of four intense, 1.5 credit modules taken by all trainees. Beyond that, trainees choose at least three courses from a series of twelve 1 and 2 credit modules (the 660 series) that teach the fundamentals of different methods for investigating the structure and function of macromolecules. These allow trainees to establish a solid theoretical and practical (some have both lab and lecture components) background in the particular areas of Biophysics relevant to their individual training goals. Research Rotations performed during the first year of training provides trainees opportunities both to obtain additional practical experience and to identify potential laboratories for their thesis research. Finally, our Training Program prepares trainees to be successful in the highly collaborative atmosphere of modern bioscience. All our courses are organized into Work Groups in which trainees do assignments in a collaborative fashion. This encourages trainees from diverse basic disciplines (cell biology to physics) to work together and learn from each other as well as attack problems in an interdisciplinary fashion. Our seminar course not only introduces trainees to research that spans the broad range of modern biophysics, but also helps them develop the oral communication skills critical to their professional success.

Core Biophysics Modules

Methods in Biophysics

 

Sample Curricula for MCBP Trainees

The following curricula come from three different students in our training program who are receiving their PhDs from three separate departments or programs (Biochemistry and Biophysics, Chemistry, and Bioinformatics and Computational Biology).  Classes that are only 1/3 of a semester are indicated with an asterisk.

Student 1:  Entered the Biochemistry and Biophysics PhD Program and matriculated to UNC through the BBSP program.

Fall of year 1
BBSP 901 (Research in BBSP – rotations)
BBSP 902 (Seminar in BBSP-First Year Group / RCR Training)
BIOC 650 (Principles of Molecular Thermodynamics)*
BIOC 651 (Macromolecular Interactions and Forces)*
BIOC 652 (Macromolecular Dynamics)*
CHEM 732 (Macromolecular Structure)

Spring of year 1
BBSP 901 (Research in BBSP – rotations)
BBSP 902 (Seminar in BBSP-First Year Group / RCR Training)
BIOC 662 (Macromolecular Interactions)*
BIOC 667 (Macromolecular crystallographic methods)*
BIOC 670 (Structural Bioinformatics)*
BIOC 704 (Seminars in Biophysics)

Fall of year 2
BIOC 712 (Grant Writing Class)

 

Student 2: Entered the Chemistry PhD Program and matriculated to UNC through the Chemistry department.  This person will receive a certificate in Biophysics in addition to their PhD from Chemistry.

Fall of year 1
BIOC 601 (Enzyme Properties)
BIOC 650 (Principles of Molecular Thermodynamics)*
BIOC 651 (Macromolecular Interactions and Forces)*
BIOC 652 (Macromolecular Dynamics)*
CHEM 701 (Intro to Lab Safety)
CHEM 731 (Seminars in Biological Chemistry)
CHEM 732 (Macromolecular Structure)
Participated in RCR training with BBSP First Year Group

Spring of year 1
BIOC 662 (Macromolecular Interactions)*
BIOC 663A (Macromolecular NMR)*
BIOC 663A (Macromolecular NMR Lab)*
BIOC 664 (Macromolecular Spectroscopy)*
BIOC 704 (Seminars in Biophysics)
BIOC 730 (Chemical Biology)
CHEM 731 (Seminars in Biological Chemistry)
Participated in RCR training with BBSP First Year Group

Fall of year 2
BIOC 712 (Grant Writing Class)

 

Student 3: Entered the Bioinformatics and Computational Biology PhD Program and matriculated to UNC through the BBSP program.  This person will receive a certificate in Biophysics in addition to their PhD from BCB.

Fall of year 1
BBSP 901 (Research in BBSP – rotations)
BBSP 902 (Seminar in BBSP-First Year Group / RCR Training)
BIOC 650 (Principles of Molecular Thermodynamics)*
BIOC 651 (Macromolecular Interactions and Forces)*
BIOC 652 (Macromolecular Dynamics)*
BCB 710 (Bioinformatics Colloquium)
BCB 720 (Intro to Statistical Modeling)

Spring of year 1
BBSP 901 (Research in BBSP – rotations)
BBSP 902 (Seminar in BBSP-First Year Group / RCR Training)
BIOC 662 (Macromolecular Interactions)*
BIOC 670 (Structural Bioinformatics)*
BIOC 704 (Seminars in Biophysics)
BCB 710 (Bioinformatics Colloquium)
BCB 712 (Bioinformatics Databases)*
BCB 715 (Mathematical approaches to modeling signaling pathways)*

Fall of year 2
BIOC 712 (Grant Writing Class)