BIOC 663A and 663B Macromolecular NMR: Theory and Practice
Instructors: Sharon Campbell (Course Coordinator) campbesl@med.unc.edu, Qi Zhang (qi_zhang@med.unc.edu) Stu Parnham (stitch@email.unc.edu),
Offered in odd numbered years
See Connect Carolina for current dates, meeting pattern, and location.
*Labs – 3 hours per week in Marsico Hall (time and day TBA). Cross listed as Chem 734.
UNC Biomolecular NMR Laboratory
Topics:
- Pulse NMR: Basic principles and methods
- Laboratory: Simple experiments in D2O
- Spin relaxation: The theory and measurement of T1 and T2
- Laboratory: Data management and treatment
- Spin coupling: Scalar (through-bond) coupling
- Laboratory: A simple protein in water
- Dipolar (through-space) coupling (the NOE) and polarization transfer
- Laboratory: 1D NOE
- 2D homonuclear NMR: Principles and methods
- Laboratory: 2D COSY and NOESY in D2O and H2O