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Instructor: Sharon Campbell (sharon_campbell@med.unc.edu)

Dates: 2nd third of spring semester (2/14/2022-3/25/2022); Offered in even numbered years

Time: MWF 3:30pm-5:00pm

Location: TBD

Prerequisite, BIOC 663A/CHEM 734 and associated NMR lab (BIOC 663B/ CHEM 734 or permission of the course director). Consists of both lecture and lab format. The objectives of this course are to introduce students to advanced topics in macromolecular NMR spectroscopy. Topics include understanding fundamental concepts associated with two-dimensional double resonance spectroscopy as well as triple resonance 3D NMR spectroscopy (understanding pulse sequences, setting up experiments on the spectrometer, processing data, and assigning resonances on a small protein).